Weight reduction and dietary improvements in a clusterrandomised controlled trial for adults with intellectual disabilities

  • Helen K. Røstad-Tollefesen Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway; and Baerum Municipality, Housing, Activity and Organized Work, Health, and Welfare, Baerum, Norway
  • Svein O. Kolset Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
  • Kjetil Retterstøl Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway;; and Lipid Clinic, Oslo University Hospital, Oslo, Norway
  • Heidi Hesselberg Baerum Municipality, Housing, Activity and Organized Work, Health, and Welfare, Baerum, Norway
  • Marianne Nordstrøm Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway; Frambu Resource Centre for Rare Disorders, Siggerud, Norway; and Unit for Inborn and Hereditary Neuromuscular Disorders, Department of Neurology, Oslo University Hospital, Oslo, Norway
Keywords: intellectual disability, behaviour change techniques, weight reduction, dietary habits, fruit, vegetables

Abstract

Background: People with intellectual disabilities (IDs) have an increased risk of obesity and health concerns related to their nutritional status and dietary intake.

Objective: To assess the effectiveness of a multi-component intervention on weight, waist circumference (WC), clinical health parameters and dietary habits in a group of overweight and obese adults with mild-to-moderate ID.

Design: A 7-month cluster-randomised trial and a 7-month follow-up of the intervention group after the end of intervention when the group received usual care. The intervention consisted of monthly dietary-group courses tailored to the participants’ cognitive abilities and practical skills, monthly nutritional courses for staff, use of behaviour change techniques and nudging. The control group received usual care during the intervention.

Results: There were 32 participants aged 22–61 years: 15 in the intervention group and 17 in the control group. After 7 months, a non-significant weight difference (median difference = −1.25 kg; 95% confidence interval [CI] = −2.00; 0.95 vs. +1.00 kg; CI = −1.15; 3.00, P = 0.08) and a significant WC difference were observed between the intervention and control groups (median difference = −3.75 cm; CI: −7.68; 0.11 vs. 0 cm; CI = −3.99; 1.00, P = 0.03), respectively. The median reduction in WC continued in the intervention group during the 7-month follow-up (median difference = −7.50 cm; CI: −13.57; −3.16, P = 0.002). A significant difference in frequency intake of fruit (P = 0.03) and berries (P = 0.004) was observed between the groups after 7 months, supported by a significant increase in measured serum-carotenoid levels in the intervention group after 7 months (median difference = 0.26 mmol/L; CI: −0.12; 0.52, P = 0.007).

Conclusions: A significant difference in WC was observed between the groups, accompanied by changes in blood parameters and dietary habits.

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References


1.
Ng N, Flygare Wallén E, Ahlström G. Mortality patterns and risk among older men and women with intellectual disability: a Swedish national retrospective cohort study. BMC Geriatr 2017; 17: 269. doi: 10.1186/s12877-017-0665-3


2.
Sandberg M, Ahlstrom G, Kristensson J. Patterns of somatic diagnoses in older people with intellectual disability: a Swedish eleven year case-control study of inpatient data. J Appl Res Intellect Disabil 2017; 30: 157–71. doi: 10.1111/jar.12230


3.
Zwack CC, McDonald R, Tursunalieva A, Lambert GW, Lambert EA. Exploration of diet, physical activity, health knowledge and the cardiometabolic profile of young adults with intellectual disability. J Intellect Disabil Res 2022; 66: 517–32. doi: 10.1111/jir.12917


4.
Flygare Wallen E, Ljunggren G, Carlsson AC, Pettersson D, Wandell P. High prevalence of diabetes mellitus, hypertension and obesity among persons with a recorded diagnosis of intellectual disability or autism spectrum disorder. J Intellect Disabil Res 2018; 62: 269–80. doi: 10.1111/jir.12462


5.
Draheim CC, Stanish HI, Williams DP, McCubbin JA. Dietary intake of adults with mental retardation who reside in community settings. Am J Ment Retard 2007; 112: 392–400. doi: 10.1352/0895-8017(2007)112[0392:Dioawm]2.0.Co;2


6.
Hove O. Weight survey on adult persons with mental retardation living in the community. Res Dev Disabil 2004; 25: 9–17.


7.
Nordstrøm M, Retterstøl K, Hope S, Kolset SO. Nutritional challenges in children and adolescents with Down syndrome. Lancet Child Adolesc Health 2020; 4: 455–64. doi: 10.1016/s2352-4642(19)30400-6


8.
Bertoli S, Battezzati A, Merati G, Margonato V, Maggioni M, Testolin G, et al. Nutritional status and dietary patterns in disabled people. Nutr Metab Cardiovasc Dis 2006; 16: 100–12. doi: 10.1016/j.numecd.2005.05.007


9.
Hamzaid NH, O’Connor HT, Flood VM. Observed dietary intake in adults with intellectual disability living in group homes. Nutrients 2019; 12: 1–12. doi: 10.3390/nu12010037


10.
Nordstrom M, Paus B, Andersen LF, Kolset SO. Dietary aspects related to health and obesity in Williams syndrome, Down syndrome, and Prader-Willi syndrome. Food Nutr Res 2015; 59: 25487. doi: 10.3402/fnr.v59.25487


11.
Ptomey L, Goetz J, Lee J, Donnelly J, Sullivan D. Diet quality of overweight and obese adults with intellectual and developmental disabilities as measured by the healthy eating index-2005. J Dev Phys Disabil 2013; 25: 1–17. doi: 10.1007/s10882-013-9339-z


12.
Doherty AJ, Jones SP, Chauhan U, Gibson JME. An integrative review of multicomponent weight management interventions for adults with intellectual disabilities. J Appl Res Intellect Disabil 2018; 31 Suppl 1: 39–51. doi: 10.1111/jar.12367


13.
Bazzano AT, Zeldin AS, Diab IR, Garro NM, Allevato NA, Lehrer D. The Healthy Lifestyle Change Program: a pilot of a community-based health promotion intervention for adults with developmental disabilities. Am J Prev Med 2009; 37: S201–8. doi: 10.1016/j.amepre.2009.08.005


14.
Elinder LS, Sundblom E, Zeebari Z, Bergström H. Effect and process evaluation of a structural health intervention in community residences for adults with intellectual disabilities. J Policy Pract Intellect Disabil 2018; 15: 319–28. doi: 10.1111/jppi.12262


15.
Harris L, Melville C, Murray H, Hankey C. The effects of multi-component weight management interventions on weight loss in adults with intellectual disabilities and obesity: a systematic review and meta-analysis of randomised controlled trials. Res Dev Disabil 2018; 72: 42–55. doi: 10.1016/j.ridd.2017.10.021


16.
Willems M, Waninge A, Hilgenkamp TIM, van Empelen P, Krijnen WP, van der Schans CP, et al. Effects of lifestyle change interventions for people with intellectual disabilities: systematic review and meta-analysis of randomized controlled trials. J Appl Res Intellect Disabil 2018; 31: 949–61. doi: 10.1111/jar.12463


17.
Willems M, Hilgenkamp TI, Havik E, Waninge A, Melville CA. Use of behaviour change techniques in lifestyle change interventions for people with intellectual disabilities: a systematic review. Res Dev Disabil 2017; 60: 256–68. doi: 10.1016/j.ridd.2016.10.008


18.
Marks B, Sisirak J, Chang YC. Efficacy of the HealthMatters program train-the-trainer model. J Appl Res Intellect Disabil 2013; 26: 319–34. doi: 10.1111/jar.12045


19.
Melville CA, Hamilton S, Miller S, Boyle S, Robinson N, Pert C, et al. Carer knowledge and perceptions of healthy lifestyles for adults with intellectual disabilities. J Appl Res Intellect Disabil 2009; 22: 298–306. doi: 10.1111/j.1468-3148.2008.00462.x


20.
Røstad-Tollefsen HK, Kolset SO, Retterstøl K, Hesselberg H, Nordstrøm M. Factors influencing the opportunities of supporting staff to promote a healthy diet in adults with intellectual disabilities. J Appl Res Intellect Disabil 2021; 34: 733–41. doi: 10.1111/jar.12846


21.
World Health Organization. International statistical classification of diseases and related health problems. 10th revision, Volume 1. Fifth edition, 2016. Geneva: World Health Organization; 2015. Available from: https://apps.who.int/iris/handle/10665/246208 [cited 12 December 2022].


22.
Michie S, Richardson M, Johnston M, Abraham C, Francis J, Hardeman W, et al. The behavior change technique taxonomy (v1) of 93 hierarchically clustered techniques: building an international consensus for the reporting of behavior change interventions. Ann Behav Med 2013; 46: 81–95. doi: 10.1007/s12160-013-9486-6


23.
Ruud MP, Raanaas RK, Bjelland M. Caregivers’ perception of factors associated with a healthy diet among people with intellectual disability living in community residences: a Concept mapping method. Res Dev Disabil 2016; 59: 202–10. doi: 10.1016/j.ridd.2016.09.006


24.
Helsedirektoratet [Norwegian Directorate of Health]. Helsedirektoratets kostråd Rapport IS-2377E [The Norwegian Dietary Quidlines]: Norwegian Directorate of Health; 2015. Available from: https://www.helsedirektoratet.no/brosjyrer/helsedirektoratets-kostrad-brosjyre-og-plakat/Helsedirektoratets%20kostråd%20-%20engelsk.pdf/_/attachment/inline/80f68126-68af-4cec-b2aa-d04069d02471:dcb8efdbe6b6129470ec4969f6639be21a8afd82/Helsedirektoratets%20kostråd%20-%20engelsk.pdf [cited 11 December 2022].


25.
Willems M, Waninge A, de Jong J, Hilgenkamp TIM, van der Schans CP. Exploration of suitable behaviour change techniques for lifestyle change in individuals with mild intellectual disabilities: a Delphi study. J Appl Res Intellect Disabil 2019; 32: 543–57. doi: 10.1111/jar.12548


26.
Karde AS. Food and well-being 2014. Available from: https://min.helsekompetanse.no/course/view.php?id=151 [cited 1 December 2022].


27.
World Health Organization. Obesity: preventing and managing the global epidemic. Report of a WHO Consultation (WHO Technical Report Series 894). Geneva: World Health Organization; 2000. Available from: https://apps.who.int/iris/handle/10665/63854 [cited 12 December 2022].


28.
Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, et al. Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Circulation 2005; 111: 697–716. doi: 10.1161/01.Cir.0000154900.76284.F6


29.
Lillegaard IT, Overby NC, Andersen LF. Evaluation of a short food frequency questionnaire used among Norwegian children. Food Nutr Res 2012; 56. doi: 10.3402/fnr.v56i0.6399


30.
Visseren FLJ, Mach F, Smulders YM, Carballo D, Koskinas KC, Bäck M, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J 2021; 42: 3227–337. doi: 10.1093/eurheartj/ehab484


31.
Mach F, Baigent C, Catapano AL, Koskinas KC, Casula M, Badimon L, et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk. Eur Heart J 2020; 41: 111–88. doi: 10.1093/eurheartj/ehz455


32.
National Institute for Health and Care Excellence (NICE). Type 2 diabetes: prevention in people at high risk. Public health guideline [PH38]. London, UK: National Institute for Health and Care Excellence; 2012. Available from: https://www.nice.org.uk/guidance/ph38 [cited 12 December 2022].


33.
Hintze LJ, Goldfield G, Seguin R, Damphousse A, Riopel A, Doucet É. The rate of weight loss does not affect resting energy expenditure and appetite sensations differently in women living with overweight and obesity. Physiol Behav 2019; 199: 314–21. doi: 10.1016/j.physbeh.2018.11.032


34.
Headland ML, Clifton PM, Keogh JB. Effect of intermittent energy restriction on flow mediated dilatation, a measure of endothelial function: a short report. Int J Environ Res Public Health 2018; 15: 1–10. doi: 10.3390/ijerph15061166


35.
Bergstrom H, Hagstromer M, Hagberg J, Elinder LS. A multi-component universal intervention to improve diet and physical activity among adults with intellectual disabilities in community residences: a cluster randomised controlled trial. Res Dev Disabil 2013; 34: 3847–57. doi: 10.1016/j.ridd.2013.07.019


36.
Lally P, Beeken RJ, Wilson R, Omar R, Hunter R, Fovargue S, et al. A manualised weight management programme for adults with mild–moderate intellectual disabilities affected by excess weight: a randomised controlled feasibility trial (Shape Up-LD)*. J Appl Res Intellect Disabil 2022; 35: 112–22. doi: 10.1111/jar.12922


37.
Ferreira FG, Juvanhol LL, da Silva DCG, Longo GZ. Visceral adiposity index is a better predictor of unhealthy metabolic phenotype than traditional adiposity measures: results from a population-based study. Public Health Nutr 2019; 22: 1545–54. doi: 10.1017/s136898001800335x


38.
Humphries K, Pepper A, Traci MA, Olson J, Seekins T. Nutritional intervention improves menu adequacy in group homes for adults with intellectual or developmental disabilities. Disabil Health J 2009; 2: 136–44. doi: 10.1016/j.dhjo.2009.01.004


39.
Brevik A, Andersen LF, Karlsen A, Trygg KU, Blomhoff R, Drevon CA. Six carotenoids in plasma used to assess recommended intake of fruits and vegetables in a controlled feeding study. Eur J Clin Nutr 2004; 58: 1166–73. doi: 10.1038/sj.ejcn.1601945


40.
Carlsen MH, Karlsen A, Lillegaard IT, Gran JM, Drevon CA, Blomhoff R, et al. Relative validity of fruit and vegetable intake estimated from an FFQ, using carotenoid and flavonoid biomarkers and the method of triads. Br J Nutr 2011; 105: 1530–8. doi: 10.1017/s0007114510005246


41.
Jenab M, Slimani N, Bictash M, Ferrari P, Bingham SA. Biomarkers in nutritional epidemiology: applications, needs and new horizons. Hum Genet 2009; 125: 507–25. doi: 10.1007/s00439-009-0662-5


42.
Hsieh K, Rimmer JH, Heller T. Obesity and associated factors in adults with intellectual disability. J Intellect Disabil Res 2014; 58: 851–63. doi: 10.1111/jir.12100


43.
Shah RV, Murthy VL, Allison MA, Ding J, Budoff M, Frazier-Wood AC, et al. Diet and adipose tissue distributions: the multi-ethnic study of atherosclerosis. Nutr Metab Cardiovasc Dis 2016; 26: 185–93. doi: 10.1016/j.numecd.2015.12.012


44.
Gepner Y, Shelef I, Schwarzfuchs D, Zelicha H, Tene L, Yaskolka Meir A, et al. Effect of distinct lifestyle interventions on mobilization of fat storage pools: CENTRAL magnetic resonance imaging randomized controlled trial. Circulation 2018; 137: 1143–57. doi: 10.1161/circulationaha.117.030501


45.
Scottish Intercollegiate Guideline Network (SIGN). Management of obesity: a national clinical guideline. Edinburgh, UK: Scottish Intercollegiate Guideline Network (SIGN); 2010. Available from: https://www.sign.ac.uk/assets/sign115.pdf [cited 8 December 2022].


46.
National Institute for Health and Care Excellence (NICE). Obesity: identification, assessment and management of overweight and obesity in children, young people and adults. Clinical guidline [CG189]. London, UK: National Institute for Health and Care Excellence 2014. Available from: www.nice.org.uk/guidance/cg189 [cited 8 December 2022].


47.
Bergstrom H, Wihlman U. The role of staff in health promotion in community residences for people with intellectual disabilities: variation in views among managers and caregivers. J Intellect Disabil 2011; 15: 167–76. doi: 10.1177/1744629511424833
Published
2023-12-19
How to Cite
Røstad-Tollefesen H. K., Kolset S. O., Retterstøl K., Hesselberg H., & Nordstrøm M. (2023). Weight reduction and dietary improvements in a clusterrandomised controlled trial for adults with intellectual disabilities. Food & Nutrition Research, 67. https://doi.org/10.29219/fnr.v67.9505
Section
Original Articles