Role of intestinal microecology in the regulation of energy metabolism by dietary polyphenols and their metabolites

  • Shaoling Lin College of Food Science, Fujian Agriculture and Forestry University
  • Zhengyu Wang College of Food Science, Fujian Agriculture and Forestry University
  • Ka-Lung Lam School of Life Sciences, The Chinese University of Hong Kong
  • Shaoxiao Zeng College of Food Science, Fujian Agriculture and Forestry University
  • Bee K. Tan Departments of Cardiovascular Sciences, University of Leicester
  • Jiamiao Hu College of Food Science, Fujian Agriculture and Forestry University
Keywords: polyphenols, gut microecology, energy metabolism

Abstract

Background: Polyphenols are a class of plant secondary metabolites with a variety of physiological functions. Polyphenols and their intestinal metabolites could greatly affect host energy metabolism via multiple mechanisms.

Objective: The objective of this review was to elaborate the role of intestinal microecology in the regulatory effects of dietary polyphenols and their metabolites on energy metabolism.

Methods: In this review, we illustrated the potential mechanisms of energy metabolism regulated by the crosstalk between polyphenols and intestinal microecology including intestinal microbiota, intestinal epithelial cells, and mucosal immune system.

Results: Polyphenols can selectively regulate the growth of susceptible microorganisms (eg. reducing the ratio of Firmicutes to Bacteroides, promoting the growth of beneficial bacteria and inhibiting pathogenic bacteria) as well as alter bacterial enzyme activity. Moreover, polyphenols can influence the absorption and secretion of intestinal epithelial cells, and alter the intestinal mucosal immune system.

Conclusion: The intestinal microecology play a crucial role for the regulation of energy metabolism by dietary polyphenols.

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References


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Published
2019-02-14
How to Cite
1.
Lin S, Wang Z, Lam K-L, Zeng S, Tan B, Hu J. Role of intestinal microecology in the regulation of energy metabolism by dietary polyphenols and their metabolites. fnr [Internet]. 2019Feb.14 [cited 2019Mar.19];630. Available from: https://foodandnutritionresearch.net/index.php/fnr/article/view/1518
Section
Review Articles