Low glycemic load after digestion of native starch from the indigenous tuber Belitung Taro (Xanthosoma sagittifolium) in a dynamic in vitro model of the upper GI tract (TIM-1)
Abstract
Background: Low glycemic foods are beneficial for people with type II diabetes. At the same time, sustained glucose release is also beneficial for people suffering from glycogen storage diseases. Taro (Xanthosoma sagittifolium) is a tuber indigenous to Indonesia, which has starch as the major storage carbohydrate.
Objective: The aim of the current study was to determine the speed of digestion of native and modified taro starch, compared to free glucose and wheat starch.
Design: This was investigated in a validated, dynamic computer-controlled in vitro model of the stomach and small intestine (TIM-1). Samples were taken from the dialysate, which reflected glucose absorbed in the blood stream.
Results: Native taro starch showed a ~1.5-fold reduced digestibility compared to glucose and a ~ 1.35-fold compared to wheat starch. In addition, digestion of native taro starch was moved towards the ileum, and later in time compared to glucose and wheat. With modified taro starch, these effects were not observed.
Conclusion: In conclusion, native taro starch showed a lower glycemic load than wheat starch and modified taro starch and could be used as a substitute for refined foods by diabetics and people suffering from other glucose metabolic diseases.
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References
- Kreike CM, Van Eck HJ, Lebot V. Genetic diversity of taro, Colocasia esculenta (L.) Schott, in Southeast Asia and the Pacific. Theor Appl Genet 2004; 109(4): 761–8. doi: 10.1007/s00122-004-1691-z
- Prana MS, Kuswara T. Budidaya Talas: diversifikasi untuk Menunjang Ketahanan Pangan Nasional (Taro Cultivation: Diversification to Support National Food Security). Bogor: Medikom Pustaka Mandiri; 2002.
- Asha Devi A. Genetic diversity analysis in taro using molecular markers – an overview. J Root Crops 2012; 38(1): 15–25.
- Onwueme IC. The tropical tuber crops – Yams, cassava, sweet potato and cocoyams. Chichester, UK: John Wiley and Sons; 1978.
- Solossa AH, Sastrahidayat IR, Hakim L. Home gardens of the local community surrounding Lake Ayamaru, West Papua province, and its consequences for tourism development and lake conservation. J Biodiv Environ Sci 2017; 3(3): 1–11.
- Bellmann S, Minekus M, Sanders P, Bosgra S, Havenaar R. Human glycemic response curves after intake of carbohydrate foods are accurately predicted by combining in vitro gastrointestinal digestion with in silico kinetic modeling. Clin Nutr Exp 2018; 17: 8–22. doi: 10.1016/j.yclnex.2017.10.003
- Bjarnason IT, Sherwood RA. Clinical biochemistry of the gastrointestinal tract. In: Marshall WJ, Lapsley M, Day AP, Ayling RM, editors. Clinical biochemistry: metabolic and clinical aspects. 3rd ed. Churchill Livingstone, London: UK 2014; p. 214–30. doi: 10.1016/B978-0-7020-5140-1.00012-2
- American Diabetes Association Diagnosis and classification of diabetes mellitus. Diabetes Care 2014; 37 Suppl 1: S81–90. doi: 10.2337/dc14-S081
- Nalin T, Venema K, Weinstein DA, de Souza CF, Perry ID, van Wandelen MT, et al. In vitro digestion of starches in a dynamic gastrointestinal model: an innovative study to optimize dietary management of patients with hepatic glycogen storage diseases. J Inherit Metab Dis 2015; 38(3): 529–36. doi: 10.1007/s10545-014-9763-y
- Zhao X-H, Lin Y. The impact of coupled acid or pullulanase debranching on the formation of resistant starch from maize starch with autoclaving–cooling cycles. Eur Food Res Technol 2009; 230: 179. doi: 10.1007/s00217-009-1151-8
- Fassler C, Arrigoni E, Venema K, Brouns F, Amado R. In vitro fermentability of differently digested resistant starch preparations. Mol Nutr Food Res 2006; 50(12): 1220–8. doi: 10.1002/mnfr.200600106
- Kovatcheva-Datchary P, Egert M, Maathuis A, Rajilic-Stojanovic M, de Graaf AA, Smidt H, et al. Linking phylogenetic identities of bacteria to starch fermentation in an in vitro model of the large intestine by RNA-based stable isotope probing. Environ Microbiol 2009; 11(4): 914–26. doi: 10.1111/j.1462-2920.2008.01815.x
- Rose DJ, Venema K, Keshavarzian A, Hamaker BR. Starch-entrapped microspheres show a beneficial fermentation profile and decrease in potentially harmful bacteria during in vitro fermentation in faecal microbiota obtained from patients with inflammatory bowel disease. Br J Nutr 2010; 103(10): 1514–24. doi: 10.1017/S0007114509993515
- Hamer HM, Jonkers D, Venema K, Vanhoutvin S, Troost FJ, Brummer RJ. Review article: the role of butyrate on colonic function. Aliment Pharmacol Ther 2008; 27(2): 104–19. doi: 10.1111/j.1365-2036.2007.03562.x
- Minekus M, Marteau P, Havenaar R, Huis In’t Veld JHJ. A multicompartmental dynamic computer-controlled model simulating the stomach and small intestine. Altern Lab Anim 1995; 23: 197–209.
- Bussolo de Souza C, Jonathan M, Isay Saad SM, Schols HA, Venema K. Characterization and in vitro digestibility of by-products from Brazilian food industry: cassava bagasse, orange bagasse and passion fruit peel. Bioactive Carbohydrates Dietary Fibre 2018; 16: 90–9. doi: 10.1016/j.bcdf.2018.08.001
- Fassler C, Arrigoni E, Venema K, Hafner V, Brouns F, Amado R. Digestibility of resistant starch containing preparations using two in vitro models. Eur J Nutr 2006; 45(8): 445–53. doi: 10.1007/s00394-006-0618-7
- Keller D, Van Dinter R, Cash H, Farmer S, Venema K. Bacillus coagulans GBI-30, 6086 increases plant protein digestion in a dynamic, computer-controlled in vitro model of the small intestine (TIM-1). Benef Microbes 2017; 8(3): 491–6. doi: 10.3920/BM2016.0196
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