Nutritional properties and biological activities of kiwifruit (Actinidia) and kiwifruit products under simulated gastrointestinal in vitro digestion

  • Tingting Ma
  • Tian Lan
  • Tonghui Geng
  • Yanlun Ju
  • Guo Cheng
  • Zhiluo Que
  • Guitian Gao
  • Yulin Fang
  • Xiangyu Sun
Keywords: Kiwifruit; Kiwifruit products; Nutritional properties; In vitro digestion; Digestive characteristics; Antioxidant capacity

Abstract

Background: Kiwifruit is one of the most commercialized fruits on the international market, which has notable high nutritional and medicinal value with many health benefits. In addition to being consumed fresh, numerous kiwifruit products are popular, such as kiwifruit juice, vinegar, dried slices, jam, wine, yogurt, and jelly. Although many studies have described the nutritional properties of kiwifruit, investigations on the nutritional properties of kiwifruit products remain limited, especially for kiwifruit products made from raw kiwifruit.

Methods: Nutritional properties and biological activities of kiwifruit and kiwifruit products, as well as the digestive and absorption characteristics of their nutritional substances, were investigated.

Results: Kiwifruit, juice, wine, and vinegar were observed to be rich in vitamin C (VC) and polyphenol and exhibited high biological activities, whereas dried kiwifruit slices and jam showed higher amounts of mineral elements. During oral digestion, VC and polyphenol showed similar absorption characteristics, while mineral elements exhibited a number of different trends. A good release rate of all nutritional substances was observed during stomach digestion, while the release rate decreased in serum-available, colon-available, and post-colonic fractions. Eating dried slices and jam supplied high amounts of mineral elements, while eating kiwifruit supplied the most comprehensive nutritional substances. The biological activities detected in raw foodstuffs were much higher than those detected after in vitro digestion. Furthermore, kiwifruit and wine showed the highest biological activities, while dried kiwifruit slices showed the lowest biological activities.

Conclusion: These results increased our understanding of the nutritional properties of kiwifruit and its products, providing new information and scientific recommendations to consumers for kiwifruit consumption and to producers for kiwifruit production.

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References


  1. Guo J, Yuan Y, Dou P, Yue T. Multivariate statistical analysis of the polyphenolic constituents in kiwifruit juices to trace fruit varieties and geographical origins. Food Chem 2017; 232: 552–9. doi: 10.1016/j.foodchem.2017.04.037.

  2. Ferguson A, Stanley R. Kiwifruit. In: Caballero B, ed. Encyclopedia of food sciences and nutrition. Oxford: Academic Press; 2003, pp. 3425–31.

  3. Ma TT, Sun XY, Zhao JM, You YL, Lei YS, Gao GT, et al. Nutrient compositions and antioxidant capacity of Kiwifruit (Actinidia) and their relationship with flesh color and commercial value. Food Chem 2017; 218: 294–304. doi: 10.1016/j.foodchem.2016.09.081.

  4. Giangrieco I, Proietti S, Moscatello S, Tuppo L, Battistelli A, La Cara F, et al. Influence of geographical location of orchards on green kiwifruit bioactive components. J Agric Food Chem 2016; 64: 9172–9. doi: 10.1021/acs.jafc.6b03930

  5. Chang C, Lin Y, Lu Y, Liu Y, Liu J. Kiwifruit improves bowel function in patients with irritable bowel syndrome with constipation. Asia Pac J Clin Nutr 2010; 19: 451–7. doi: 10.6133/apjcn.2010.19.4.01.

  6. Abe D, Saito T, Kubo Y, Nakamura Y, Sekiya K. A fraction of unripe kiwi fruit extract regulates adipocyte differentiation and function in 3T3-L1 cells. BioFactors 2010; 36: 52–9. doi: 10.1002/biof.70.

  7. Edmunds S, Roy N, Love D, Laing W. Kiwifruit extracts inhibit cytokine production by lipopolysaccharide-activated macrophages, and intestinal epithelial cells isolated from IL10 gene deficient mice. Cell Immunol 2011; 270: 70–9. doi: 10.1016/j.cellimm.2011.04.004.

  8. Jung K, Song T, Han D, Kim I, Kim Y, Lee C. Cardiovascular protective properties of kiwifruit extracts in vitro. Biol Pharm Bull 2005; 28: 1782–5. doi: 10.1248/bpb.28.1782.

  9. Motohashi N, Shirataki Y, Kawase M, Tani S, Sakagami H, Satoh K, et al. Cancer prevention and therapy with kiwifruit in Chinese folklore medicine: a study of kiwifruit extracts. J Ethnopharmacol 2002; 81: 357–64. doi: 10.1016/S0378-8741(02)00125-3.

  10. Nishiyama I, Yamashita Y, Yamanaka M, Shimohashi A, Fukuda T, Oota T. Varietal difference in vitamin C content in the fruit of kiwifruit and other actinidia species. J Agric Food Chem 2004; 52: 5472–5. doi: 10.1021/jf049398z.

  11. Du G, Li M, Ma F, Liang D. Antioxidant capacity and the relationship with polyphenol and vitamin C in Actinidia fruits. Food Chem 2009; 113: 557–62. doi: 10.1016/j.foodchem.2008.08.025.

  12. Santoni F, Paolini J, Barboni T, Costa J. Relationships between the leaf and fruit mineral compositions of Actinidia deliciosa var. Hayward according to nitrogen and potassium fertilization. Food Chem 2014; 147: 269–71. doi: 10.1016/j.foodchem.2013.09.154.

  13. Zhang Z, Guo K, Bai Y, Dong J, Gao Z, Yuan Y, et al. Identification, synthesis, and safety assessment of forchlorfenuron (1-(2-Chloro-4-pyridyl)-3-phenylurea) and its metabolites in kiwifruits. J Agric Food Chem 2015; 63: 3059–66. doi: 10.1021/acs.jafc.5b01100.

  14. Aschoff J, Kaufmann S, Kalkan O, Neidhart S, Carle R, Schweiggert R. In vitro bioaccessibility of carotenoids, flavonoids, and vitamin C from differently processed oranges and orange juices [Citrus sinensis (L.) Osbeck]. J Agric Food Chem 2015; 63: 578–87. doi: 10.1021/jf505297t.

  15. Butts-Wilmsmeyer CJ, Mumm RH, Rausch KD, Kandhola G, Yana N, Happ MM, et al. Changes in phenolic acid content in maize during food product processing. J Agric Food Chem 2018; 66: 3378–85. doi: 10.1021/acs.jafc.7b05242.

  16. Lingua M, Wunderlin D, Baroni M. Effect of simulated digestion on the phenolic components of red grapes and their corresponding wines. J Funct Foods 2018; 44: 86–94. doi: 10.1016/j.jff.2018.02.034.

  17. Rodrigo M, Cilla A, Barberá R, Zacarías L. Carotenoid bioaccessibility in pulp and fresh juice from carotenoid-rich sweet oranges and mandarins. Food Funct 2015; 6: 1950–9. doi:10.1039/c5fo00258c.

  18. Minekus M, Alminger M, Alvito P, Ballance S, Bohn T, Bourlieu C. A standardised static in vitro digestion method suitable for food-an international consensus. Food Funct 2014; 5: 1113–24. doi: 10.1039/c3fo60702j.

  19. Alminger M, Aura A, Bohn T, Dufour C, El S, Gomes A, et al. In vitro models for studying secondary plant metabolite digestion and bioaccessibility. Compr Rev Food Sci F 2014; 13: 413–36. doi: 10.1111/1541-4337.12081.

  20. Ren M, Wang X, Tian C, Li X, Zhang B, Song X, et al. Characterization of organic acids and phenolic compounds of cereal vinegars and fruit vinegars in China. J Food Process Pres 2016; 41: 1–8. doi: 10.1111/jfpp.12937.

  21. Li W, Yuan L, Xiao X, Yang X. Dehydration of kiwifruit (Actinida deliciosa) slices using heat pipe combining with impingement technology. Int J Food Eng 2016; 12: 265–76. doi: 10.1515/ijfe-2015-0165.

  22. Luo A, Liu X, Ren Y, Kou L. Study on brewing technology of kiwi-fruit dry wine. J Chin Inst Food Sci Tech 2004; 4: 5–11. doi: 10.16429/j.1009-7848.2004.02.002.

  23. Bengtsson A, Alminger M, Svanberg U. In vitro bioaccessibility of β-carotene from heat-processed orange-fleshed sweet potato. J Agric Food Chem 2009; 57: 9693–898. doi: 10.1021/jf901692r.

  24. The national standard of China, Ministry of agriculture notice No. 869-2-2007. Food safety detection of genetically modified organisms and derived products Method of target protein digestive stability in simulative gastric and intestinal fluid. 2007. Available from: http://down.foodmate.net/wap/index.php?moduleid=23&itemid=11976.

  25. Corrêa R, Haminiuk C, Barros L, Dias M, Calhelha R, Kato C, et al. Stability and biological activity of Merlot (Vitis vinifera) grape pomace phytochemicals after simulated in vitro gastrointestinal digestion and colonic fermentation. J Funct Foods 2017; 36: 410–17. doi: 10.1016/j.jff.2017.07.030.

  26. Fu X, Cao C, Ren B, Zhang B, Huang Q, Li C. Structural characterization and in vitro fermentation of a novel polysaccharide from Sargassum thunbergii and its impact on gut microbiota. Carbohyd Polym 2018; 183: 230–9. doi: 10.1016/j.carbpol.2017.12.048.

  27. The national standard of China. GB 5009.86-2016. Determination of vitamin C in food. 2016. Available from: http://down.foodmate.net/wap/index.php?moduleid=23&itemid=49335.

  28. Xiang J, Apea-Bah F, Ndolo V, Katundu M, Beta T. Profile of phenolic compounds and antioxidant activity of finger millet varieties. Food Chem 2019; 275: 361–8. doi: 10.1016/j.foodchem.2018.09.120.

  29. Sun X, Ma T, Han L, Huang W, Zhan J. Effects of copper pollution on the phenolic compound contents, color and antioxidant activity of wine. Molecules 2017; 22(5): 726. doi: 10.3390/molecules22050726.

  30. Ma T, Sun X, Tian C, Luo J, Zheng C, Zhan J. Enrichment and purification of polyphenol extract from Sphallerocarpus gracilis stems and leaves and in vitro evaluation of DNA damage-protective activity and inhibitory effects of α-amylase and α-glucosidase. Molecules 2015; 20: 21442–57. doi: 10.3390/molecules201219780.

  31. Gumienna M, Lasik M, Czarnecki Z. Bioconversion of grape and chokeberry wine polyphenols during simulated gastrointestinal in vitro digestion. Int J Food Sci Nutr 2011; 62(3): 226–33. doi: 10.3109/09637486.2010.532115.

  32. Yi J, Kebede B, Grauwet T, Loey A, Hu X, Hendrickx M. Comparing the impact of high-pressure processing and thermal processing on quality of ‘Hayward’ and ‘Jintao’ kiwifruit purée: Untargeted headspace fingerprinting and targeted approaches. Food Bioprocess Tech 2016; 9: 2059–69. doi: 10.1007/s11947-016-1783-1.

  33. Celep E, Charehsaz M, Akyüz S, Acar E, Yesilada E. Effect of in vitro gastrointestinal digestion on the bioavailability of phenolic components and the antioxidant potentials of some Turkish fruit wines. Food Res Int 2015; 78: 209–15. doi: 10.1016/j.foodres.2015.10.009.

  34. Schulz M, Biluca F, Gonzaga L, Borges G, Vitali L, Micke G, et al. Bioaccessibility of bioactive compounds and antioxidant potential of juçara fruits (Euterpe edulis Martius) subjected to in vitro gastrointestinal digestion. Food Chem 2017; 228: 447–54. doi: 10.1016/j.foodchem.2017.02.038.

  35. Souza L, Souza T, Santana F, Araujo R, Teixeira L, Santos D, et al. Determination and in vitro bioaccessibility evaluation of Ca, Cu, Fe, K, Mg, Mn, Mo, Na, P and Zn in linseed and sesame. Microchem J 2018; 137: 8–14. doi: 10.1016/j.microc.2017.09.010.

  36. Suliburska J, Krejpcio, Z. Evaluation of the content and bioaccessibility of iron, zinc, calcium and magnesium from groats, rice, leguminous grains and nuts. J Food Sci Tech 2011; 51: 589–94. doi: 10.1007/s13197-011-0535-5.

  37. Xiang J, Li W, Ndolo V, Beta T. A comparative study of the phenolic compounds and in vitro antioxidant capacity of finger millets from different growing regions in Malawi. J Cereal Sci 2019; 87: 143–9. doi: 10.1016/j.jcs.2019.03.016.

  38. Yang P, Yuan C, Wang H, Han F, Liu Y, Wang L, et al. Stability of anthocyanins and their degradation products from cabernet sauvignon red wine under gastrointestinal ph and temperature conditions. Molecules 2018; 23: 354. doi: 10.3390/molecules23020354.

  39. Kwon Y, Apostolidis E, Shetty K. Inhibitory potential of wine and tea against α-amylase and α-glucosidase for management of hyperglycemia linked to type 2 diabetes. J Food Biochem 2008; 32: 15–31. doi: 10.1111/j.1745-4514.2007.00165.x.

  40. The national standard of China. GB 2763-2014. National food safety standard – maximum residue limits for pesticides in food. 2014. Available from: http://dbpub.cnki.net/grid2008/dbpub/Detail.aspx?DBName=SCSF&FileName=SCSF00042227&QueryID=1&CurRec=1.

  41. Moreno-Indias I, Sánchez-Alcoholado L, Pérez-Martínez P, Andrés-Lacueva C, Cardona F, Tinahones F, et al. Red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients. Food Funct 2016; 7: 1775–87. doi: 10.1039/C5FO00886G.

  42. Queipo-Ortuño M, Boto-Ordonez M, Murri M, Gomez-Zumaquero J, Clemente-Postigo M, Estruch R, et al. Influence of red wine polyphenols on the gut microbiota ecology and biochemical biomarkers. Am J Clin Nutr 2012; 95: 1323–34. doi: 10.3945/ajcn.111.027847.

  43. Shi C, Sun Y, Zheng Z, Zhang X, Song K, Jia Z, et al. Antimicrobial activity of syringic acid against Cronobacter sakazakii and its effect on cell membrane. Food Chem 2016; 197: 100–6. doi: 10.1016/j.foodchem.2015.10.100.

  44. Montoya C, Saigeman S, Rutherfurd S, Moughan P. The digestion of kiwifruit (Actinidia deliciosa) fibre and the effect of kiwifruit on the digestibility of other dietary nutrients. Food Chem 2016; 197: 539–45. doi: 10.1016/j.foodchem.2015.10.136.

  45. National health and family planning commission of China. Dietary guidelines for Chinese residents. 2016. [cited 2016 May 13]; Available from: http://dg.cnsoc.org/index.html.

  46. Ma TT, Lan T, Ju YL, Cheng G, Que Z, Geng T, et al. Comparison on the nutritional properties and biological activities of kiwifruit (Actinidia) and their different forms products: how to make kiwifruit more nutritious and functional. Food Funct 2019; 10: 1317–29. doi: 10.1039/C8FO02322K.

Published
2019-04-08
How to Cite
1.
Ma T, Lan T, Geng T, Ju Y, Cheng G, Que Z, Gao G, Fang Y, Sun X. Nutritional properties and biological activities of kiwifruit (<em>Actinidia</em>) and kiwifruit products under simulated gastrointestinal <em>in vitro</em&gt; digestion. fnr [Internet]. 2019Apr.8 [cited 2019Oct.19];630. Available from: https://foodandnutritionresearch.net/index.php/fnr/article/view/1674
Section
Original Articles